Teratogenic Effect of Congenital Toxoplasmosis in Chicken Embryo
نویسندگان
چکیده
منابع مشابه
Toxopain-1 is critical for infection in a novel chicken embryo model of congenital toxoplasmosis.
We tested the hypothesis that cathepsins and specifically toxopain-1, a cathepsin B, play a critical role in the pathogenesis of toxoplasmosis. We found that inhibiting the expression of toxopain-1-specific mRNA and protein by >60% significantly decreased the capacity of the parasites to multiply and invade in vitro. To relate these in vitro results to the role of toxopain-1 in pathogenesis in ...
متن کاملCongenital toxoplasmosis.
Congenital toxoplasmosis results from the transplacental transmission of the parasite Toxoplasma gondii after a maternal infection acquired in pregnancy. Prevalence of congenital infection ranges from 0.1 to 0.3 per 1000 live births. The maternal-fetal transmission rate increases with gestational age at maternal seroconversion, from less than 15% at 13 weeks of gestation to over 70% at 36 weeks...
متن کاملCongenital toxoplasmosis.
The history of toxoplasmosis began in 1923 with the F first published description of a human case, a congenitally infected baby. Toxoplasma gondii had been recognised 15 years earlier, but it was not until 1%96 that the life cycle of this protozoan parasite was understood, with the discovery that the definitive host : was any member of the cat family (fig 1).' 2 _ Despite extensive clinical and...
متن کامل[Congenital toxoplasmosis].
Since congenital toxoplasmosis was first recognized as a human infection 18 years ago, it has been found in many parts of the world, and, following the first report by Jacoby and Sagorin in 1948, over 50 cases have been recorded in the British literature. Only four of the reports from this country concern the findings in fatal cases (Cathie and Dudgeon, 1949; Valentine, 1952; Valentine, Lane, B...
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ژورنال
عنوان ژورنال: KnE Life Sciences
سال: 2017
ISSN: 2413-0877
DOI: 10.18502/kls.v3i6.1187